Skip to main content

Table 3 Analytical performance data for the determination of VPS by Method 1

From: Two novel UPLC methods utilizing two different analytical columns and different detection approaches for the simultaneous analysis of velpatasvir and sofosbuvir: application to their co-formulated tablet

Parameter

Value

Column (A)

Column (B)

Linearity and range (ng/mL)

1.0–5.0

2.5–10.0

Correlation coefficient (r)

1.0

0.9999

Slope

20,723.82

49,677.50

Intercept

− 745.284

− 21,790.770

Sy/x, SD of the residuals

346.597

1808.52

Sa, SD of the intercept

363.51

1871.66

Sb, SD of the slope

109.60

296.12

SD

0.89

0.97

%RSDa

0.888

0.97

%Errorb

0.398

0.435

LODc

0.06

0.12

LOQd

0.18

0.38

  1. aPercentage relative standard deviation
  2. bPercentage relative error
  3. cLimit of detection
  4. dLimit of quantitation