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Table 3 Analytical performance data for the determination of VPS by Method 1

From: Two novel UPLC methods utilizing two different analytical columns and different detection approaches for the simultaneous analysis of velpatasvir and sofosbuvir: application to their co-formulated tablet

Parameter Value
Column (A) Column (B)
Linearity and range (ng/mL) 1.0–5.0 2.5–10.0
Correlation coefficient (r) 1.0 0.9999
Slope 20,723.82 49,677.50
Intercept − 745.284 − 21,790.770
Sy/x, SD of the residuals 346.597 1808.52
Sa, SD of the intercept 363.51 1871.66
Sb, SD of the slope 109.60 296.12
SD 0.89 0.97
%RSDa 0.888 0.97
%Errorb 0.398 0.435
LODc 0.06 0.12
LOQd 0.18 0.38
  1. aPercentage relative standard deviation
  2. bPercentage relative error
  3. cLimit of detection
  4. dLimit of quantitation