Studied drug
|
Proposed method
|
Comparison method [11]
|
---|
Amount taken (ng/mL)
|
Amount found (ng/mL)
|
% Found
|
% Found
|
---|
Column (A)
|
Column (B)
|
Column (A)
|
Column (B)
|
Column (A)
|
Column (B)
|
---|
SFV
|
120
|
120
|
120.468
|
119.472
|
100.39
|
99.56
|
99.98
|
200
|
200
|
200.140
|
195.560
|
100.07
|
97.78
|
98.93
|
280
|
280
|
279.720
|
273.000
|
99.90
|
97.50
|
100.83
|
400
|
400
|
399.520
|
393.600
|
99.88
|
98.40
| |
600
|
600
|
588.120
|
600.420
|
98.02
|
100.07
| |
Mean
| | | | |
99.65
|
98.66
|
100.85
|
±SD
| | | | |
0.93
|
1.12
|
0.95
|
t-test
| | | | |
0.38
|
1.61
|
(2.45)*
|
F-test
| | | | |
1.04
|
1.38
|
(6.94)*
|
VPS
|
30
|
30
|
30.036
|
29.817
|
100.12
|
99.39
|
101.45
|
50
|
50
|
49.420
|
50.305
|
98.84
|
100.61
|
100.47
|
70
|
70
|
68.768
|
70.455
|
98.24
|
100.65
|
99.12
|
100
|
100
|
99.140
|
100.130
|
99.14
|
100.13
| |
150
|
150
|
149.910
|
149.100
|
99.94
|
99.40
| |
Mean
| | | | |
99.26
|
100.04
|
100.35
|
±SD
| | | | |
0.78
|
0.62
|
1.17
|
t-test
| | | | |
1.61
|
0.50
|
(2.45)*
|
F-test
| | | | |
2.25
|
3.56
|
(6.94)*
|
- Each result is the average of three separate determinations
- * The figures between parentheses are the tabulated t and F values at P = 0.05 [17]