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Table 1 Physical data of synthesized compounds (1a, 2a2g)

From: Designing, synthesis and characterization of 2-aminothiazole-4-carboxylate Schiff bases; antimicrobial evaluation against multidrug resistant strains and molecular docking

Comp Molecular formula MW calculated (g/mol) M.P (°C) Physical state Color % Yield Rf Value
1a C6H8N2O2S 172.20 175–177 Solid Off white-pale yellow 70 0.71
2a C13H12N2O2S 260.31 160–162 Crystal Light brown 50 0.61
2b C13H12N2O3S 276.31 198–199 Solid Light brown 56 0.64
2c C13H12N2O3S 276.31 195–197 Solid Orange 54 0.66
2d C13H12N2O3S 276.31 200–202 Solid Brown 60 0.69
2e C14H14N2O4S 306.33 196–198 Solid Light brown 50 0.61
2f C14H14N2O2S 274.33 190–192 Crystal Light brown 52 0.59
2g C14H14N2O3S 290.33 164–165 Crystal Light brown 62 0.60
  1. Solvent system: ethyl acetate: petroleum ether (3:1), TLC silica HF-254