|
Compound no.
|
Minimum inhibitory concentration (MIC = µM)
|
|---|
|
Bacterial strains
|
Fungal strains
|
|---|
|
B. subtilis
|
S. aureus
|
E. coli
|
C. albicans
|
A. niger
|
|---|
|
1.
|
91.74
|
11.47
|
22.94
|
11.47
|
91.74
|
|
2.
|
22.12
|
88.50
|
11.06
|
22.12
|
11.06
|
|
3.
|
4.81
|
19.23
|
9.62
|
4.81
|
2.40
|
|
4.
|
22.36
|
11.18
|
89.45
|
11.18
|
89.45
|
|
5.
|
83.47
|
10.43
|
83.47
|
10.43
|
20.87
|
|
6.
|
21.19
|
21.19
|
21.19
|
10.59
|
5.30
|
|
7.
|
21.70
|
10.85
|
86.81
|
10.85
|
86.81
|
|
8.
|
22.16
|
11.08
|
5.54
|
88.65
|
11.08
|
|
9.
|
10.59
|
21.19
|
84.75
|
10.59
|
21.19
|
|
10.
|
11.14
|
22.28
|
89.13
|
89.13
|
11.14
|
|
11.
|
20.49
|
2.56
|
20.49
|
10.25
|
81.97
|
|
12.
|
81.97
|
2.56
|
81.97
|
20.49
|
5.12
|
|
13.
|
11.77
|
23.54
|
11.77
|
23.54
|
94.16
|
|
14.
|
10.43
|
20.87
|
83.47
|
20.87
|
83.47
|
|
15.
|
83.33
|
83.33
|
10.42
|
20.83
|
20.83
|
|
16.
|
86.81
|
10.85
|
86.81
|
10.85
|
21.70
|
|
17.
|
21.70
|
86.81
|
21.70
|
10.85
|
21.70
|
|
Std.
|
4.71a
|
4.71a
|
4.71a
|
5.09b
|
5.09b
|
|
DMSO
|
NA
|
NA
|
NA
|
NA
|
NA
|
|
Broth control
|
NG
|
NG
|
NG
|
NG
|
NG
|
- The samples were incubated at 37 ± 1 °C for 24 h (bacteria), at 25 ± 1 °C for 7d (A. niger) and at 37 ± 1 °C for 48 h (C. albicans), respectively and the results were recorded in terms of MIC (the lowest concentration of test substance which inhibited the growth of microorganisms)
- Std.: aCiprofloxacin, bFluconazole; NA no activity, NG no growth
