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Table 1 The physicochemical properties of the synthesized compounds

From: Synthesis, molecular docking and biological potentials of new 2-(4-(2-chloroacetyl) piperazin-1-yl)-N-(2-(4-chlorophenyl)-4-oxoquinazolin-3(4H)-yl)acetamide derivatives

Compound no. M. formula M. W. M. P. (°C) Rf valuea % yield
1. C29H29ClN6O3 545.0 150–152 0.51 91.74
2. C28H26Cl2N6O3 565.5 162–164 0.51 76.90
3. C29H29ClN6O3 545.0 156–158 0.13 18.24
4. C30H31ClN6O3 559.1 162–164 0.53 53.03
5. C28H25Cl3N6O3 599.9 108–110 0.20 69.19
6. C29H28ClN7O5 590.0 126–128 0.19 81.53
7. C28H26ClN7O5 576.0 156–158 0.56 92.64
8. C28H26Cl2N6O3 565.5 128–130 0.43 77.08
9. C29H28ClN7O5 590.0 138–140 0.15 77.04
10. C29H29ClN6O4 561.0 156–158 0.50 59.89
11. C28H26Cl2N6O3 565.5 118–120 0.38 84.18
12. C28H25Cl2N7O5 610.4 110–112 0.57 77.70
13. C28H27ClN6O3 531.0 160–162 0.40 74.43
14. C28H25Cl3N6O3 599.9 120–122 0.29 49.42
15. C28H25Cl3N6O3 599.9 168–170 0.20 76.90
16. C28H26ClN7O5 576.0 122–124 0.24 85.78
17. C28H26ClN7O5 576.0 152–154 0.31 44.61
  1. aTLC mobile phase: benzene