Table 8 IC50 (μM) of synthesized compounds (9a and 9b)
From: Pharmacological significance of heterocyclic 1H-benzimidazole scaffolds: a review
Comp. | G. intestinalis | T. vaginalis | P. falciparum | |
|---|---|---|---|---|
D6 | W2 | |||
9a | 0.107 ± 0.017 | 3.314 ± 0.130 | > 20 | > 20 |
9b | 0.672 ± 0.020 | 0.232 ± 0.021 | 5.98 ± 0.25 | 6.12 ± 0.32 |
Metronidazole | 1.226 ± 0.125 | 0.236 ± 0.016 | – | – |
Albendazole | 0.038 ± 0.003 | 3.390 ± 0.125 | > 20 | >20 |