Table 4 In vitro antiprotozoal and anthelmintic screening results
From: Pharmacological significance of heterocyclic 1H-benzimidazole scaffolds: a review
Comp. | Microbial strains (IC50 µg/mL) | ||||||
|---|---|---|---|---|---|---|---|
GI | EH | TV | LM | TS (% reduction, 0.18 µM) | TS (% reduction, 0.37 µM) | TS (% reduction, 1.80 µM) | |
6a | 0.030 | 0.009 | 0.016 | 24.00 | 54 ± 2 | 62 ± 2 | 80 ± 3 |
6b | 0.063 | 0.019 | 0.110 | 4.10 | 44 ± 2 | 48 ± 3 | 67 ± 2 |
6c | 0.005 | 0.019 | 0.086 | 13.78 | 43 ± 3 | 50 ± 2 | 65 ± 3 |
ABZ | 0.037 | 56.6 | 1.592 | a | 58.6 ± 2 | 61.9 ± 3 | 67 ± 6 |
MTZ | 1.228 | 0.350 | 0.216 | b | b | b | b |
Pentamidine | b | b | b | 2.421 | b | b | b |