Skip to main content

Table 39 Anti-RT and anti-HIV-1 activities, cytotoxicity and selectivity index in MT-4 cells

From: Pharmacological significance of heterocyclic 1H-benzimidazole scaffolds: a review

Comp. IC50 (µM) EC50 (µM) CC50 (µM) SI
48a 0.12 ± 0.035 0.04 ± 0.01 > 221.59 > 5540
48b 0.18 ± 0.018 0.06 ± 0.02 ≥ 235.64 ≥ 3927
Nevirapine 2.55 ± 0.93 0.19 ± 0.06 > 15.02 > 79
Efavirenz 0.032 ± 0.009 0.006 ± 0.0001 > 1056 > 6.34