Table 36 Antiviral screening results of the synthesized compounds (43a-c)
From: Pharmacological significance of heterocyclic 1H-benzimidazole scaffolds: a review
Comp. | Antiviral potency IC50 (µg/mL) | |
|---|---|---|
CMV | VZV | |
43a | > 0.2 | 0.2–0.5 |
43b | 1.1–3.2 | 0.6–2.8 |
43c | 1.0–1.2 | 0.8–1.4 |
Acyclovir | – | 0.3–3.0 |
Ganciclovir | 0.9–1.5 | – |