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TableĀ 3 In vitro trypanocidal activity of synthesized compound 4a

From: Pharmacological significance of heterocyclic 1H-benzimidazole scaffolds: a review

Comp. Trypanosoma cruzi
LC50 (mM) CC50 (mM) Selectivity index (SI)
INC5 NINOA INC5 NINOA
4a 0.32 0.014 43.2 135 3085.71
Nifurtimox 0.69 0.78 25.4 36.81 32.56
Benznidazole 0.31 0.60 23.6 76.13 39.3