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Table 28 Anti-inflammatory, analgesic and kinase inhibition activities

From: Pharmacological significance of heterocyclic 1H-benzimidazole scaffolds: a review

Comp. Anti-inflammatory activity (%) Analgesic activity (%) Kinase IC50 (µM)
CDK-1 CDK-5 GSK-3
25a 7.4 4.6 42
25b 31.4 60
25c 35.8 50
Ibuprofen 38.8 50