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Table 15 In vitro susceptibility of bloodstream epimastigote

From: Pharmacological significance of heterocyclic 1H-benzimidazole scaffolds: a review

Comp. IC50 INC-5 (μM) IC50 NINOA (μM) CC50 (μM)
16a 28.672 ± 0.602 98.799 ± 1.990 134.580 ± 1.995
16b 186.230 ± 4.103 56.967 ± 0.961 90.436 ± 1.426
Nifurtimox 50.750 ± 0.839 89.804 ± 1.138 131.503 ± 0.490