Table 15 In vitro susceptibility of bloodstream epimastigote
From: Pharmacological significance of heterocyclic 1H-benzimidazole scaffolds: a review
Comp. | IC50 INC-5 (μM) | IC50 NINOA (μM) | CC50 (μM) |
|---|---|---|---|
16a | 28.672 ± 0.602 | 98.799 ± 1.990 | 134.580 ± 1.995 |
16b | 186.230 ± 4.103 | 56.967 ± 0.961 | 90.436 ± 1.426 |
Nifurtimox | 50.750 ± 0.839 | 89.804 ± 1.138 | 131.503 ± 0.490 |