Table 10 In vitro anti-leishmanial screening results
From: Pharmacological significance of heterocyclic 1H-benzimidazole scaffolds: a review
Comp. | Leishmania donovani | |||
|---|---|---|---|---|
Amastigote form | Promastigote form | |||
EC50 (μM) | CC50 (μM) | SI | EC50 (μM) | |
11a | 3.05 | > 50 | > 16.4 | 1.25 |
11b | 5.29 | 39.7 | 7.5 | 1.48 |
Miltefosine | 4.83 | 18.9 | 3.91 | 11.1 |
Amphotericin B | 0.25 | 7.57 | 30.2 | 0.22 |