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Table 10 In vitro anti-leishmanial screening results

From: Pharmacological significance of heterocyclic 1H-benzimidazole scaffolds: a review

Comp. Leishmania donovani
Amastigote form Promastigote form
EC50 (μM) CC50 (μM) SI EC50 (μM)
11a 3.05 > 50 > 16.4 1.25
11b 5.29 39.7 7.5 1.48
Miltefosine 4.83 18.9 3.91 11.1
Amphotericin B 0.25 7.57 30.2 0.22
  1. CC50 cytotoxicity, EC50 half maximal effective concentration, SI selective index (EC50/CC50)