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Table 1 In vitro inhibition of AChE/BuChE of compounds (1a and 1b)

From: Pharmacological significance of heterocyclic 1H-benzimidazole scaffolds: a review

Comp.

IC50 ± SEM (µM)

eeAChE

hAChE

BchE

1a

0.58 ± 0.06

3.68 ± 0.39

7.44 ± 1.51

1b

0.61 ± 0.07

0.13 ± 0.03

> 100

Tacrine

0.075 ± 0.02

0.52 ± 0.09

0.0098 ± 0.0002