Table 1 In vitro antimicrobial activities of compounds 1–5
Compound | Growth inhibition (%, mean ± SD)a | MIC (lg mL−1)b | |||||
|---|---|---|---|---|---|---|---|
Candida albicans | Candida parapsilosis | S. aureus | B. licheniformis | E. xiangfangensis | E. fergusonii | P. aeruginosa | |
1 | 82.3 ± 3.3 | 79.2 ± 2.6 | 2.3 | > 25 | > 25 | 3.1 | > 25 |
2 | 67.3 ± 2.1 | 72.2 ± 2.8 | > 25 | > 25 | > 25 | > 25 | > 25 |
3 | 23.6 ± 5.2 | 18.9 ± 3.7 | > 25 | > 25 | > 25 | > 25 | > 25 |
4 | 61.2 ± 3.3 | 69.5 ± 2.4 | 15.6 | > 25 | > 25 | > 25 | > 25 |
5 | 92 ± 3.9 | 90 ± 2.8 | > 25 | > 25 | > 25 | > 25 | > 25 |
Itraconazole | 54.7 ± 2.6 | 51.5 ± 4.1 | _ | _ | _ | _ | _ |
Amikacin | _ | _ | 0.523 | 0.523 | 0.523 | 0.523 | 0.523 |