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Table 1 IC50 against S. cerevisiae of the imidazole derivatives with strong antifungal activity

From: Identification of novel antifungal agents: antimicrobial evaluation, SAR, ADME–Tox and molecular docking studies of a series of imidazole derivatives

Compd.

Structure

IC50 (μM)a

1

240 ± 14.14

2

95 ± 7.07

3

220 ± 14.14

10

235 ± 7.07

15

305 ± 21.21

  1. aThe value obtained for each compound represents the mean of three independent experiments ± SD