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Table 3 Summary of stability of flibanserin in rat plasma under different storage conditions (n = 6)

From: A rapid and sensitive UPLC-MS/MS method for the determination of flibanserin in rat plasma: application to a pharmacokinetic study

Analytes

Concentration added (ng/mL)

Room temperature

4 °C

Three freeze–thaw

−20 °C

RE (%)

RSD (%)

RE (%)

RSD (%)

RE (%)

RSD (%)

RE (%)

RSD (%)

Flibanserin

800

− 13.2

8.6

3.2

4.4

7.9

7.3

10.8

7.9

8000

− 4.7

7.0

7.9

6.0

8.3

6.5

− 9.9

5.3

80,000

2.4

5.3

− 7.9

7.1

− 6.2

8.0

− 5.3

4.9