Computational approaches: discovery of GTPase HRas as prospective drug target for 1,3-diazine scaffolds

BMC Chemistry

Table 7 Lethal dose (LD₅₀) and selectivity index calculation of most active compounds

S. no.	Comp.	Lethal dose LD₅₀	Cancer cell line HCT116 (IC₅₀)	Selectivity index (LD₅₀/IC₅₀)
1.	s3	8.55	1.16	7.37
2.	s9	8.45	2.96	2.85
3.	s13	8.23	2.63	3.12
4.	s14	8.18	2.18	3.75
5.	s15	8.34	2.64	3.15
6.	s16	8.48	3.59	2.36

ISSN: 2661-801X