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Table 2 Click synthesis of 1H-1,2,3-triazoles
figure b

From: Peanut shell as a green biomolecule support for anchoring Cu2O: a biocatalyst for green synthesis of 1,2,3-triazoles under ultrasonic irradiation

Entry

R1

R2

X

Product

Yield (%)a

M.P. (°C)

Refs.

1

ph

ph

Br

3a

90

131–133

[47]

2

ph

4-NO2-ph

Br

3b

91

140–141

[48]

3

4-OMe-ph

ph

Br

3c

86

142–143

[49]

4

4-OMe-ph

4-Me-ph

Br

3d

92

149–151

[50]

5

ph

4-Me-ph

Br

3e

89

106–107

[51]

6

ph

4-Br-ph

Br

3f

93

150–152

[48]

7

4-Me-ph

4-Br-ph

Br

3g

92

202–203

[48]

8

4-OMe-ph

4-NO2-ph

Br

3h

97

167–168

[47]

9

4-CF3-ph

4-NO2-ph

Br

3i

88

215–217

[52]

10

4-Me-ph

ph

Br

3j

90

153–154

[53]

11

4-Me-ph

4-NO2-ph

Br

3k

86

159–160

[54]

12

ph

4-OMe-ph

Cl

3l

88

136–138

[49]

13

4-Me-ph

4-OMe-ph

Cl

3m

89

133–136

[51]

14

4-OMe-ph

ph

Cl

3c

88

142–143

[49]

15

ph

n-C3H7

Br

3n

64

41–42

[55]

16

ph

n-C4H9

Br

3o

65

42

[56]

17

CO2Me

ph

Br

3p

63

104–105

[57]

18

CO2Me

4-NO2-ph

Br

3q

61

189–190

[57]

  1. Reaction conditions: benzyl halide (1 mmol), arylacetylene (1.2 mmol), K2CO3 (2 mmol), NaN3 (1.2 mmol), 45 min
  2. aIsolated yield