Protective effect of blackthorn fruits (Prunus spinosa) against tartrazine toxicity development in albino Wistar rats

Table 2 Average values and standard deviation for hematological measurements of Wistar rats treated with tartrazine for 7 weeks

Parameter	Control	Group I	Group II	Group III
WBC 10⁹/l	4.8 ± 0.85ab	5.35 ± 1.38ab	3.85 ± 0.77b	5.87 ± 0.93a
LYM 10⁹/l	2.05 ± 0.44ab	2.79 ± 0.93a	1.55 ± 0.43b	3.06 ± 0.36a
MON 10⁹/l	0.45 ± 0.18a	0.15 ± 0.09b	0.26 ± 0.14ab	0.35 ± 0.21ab
NEU 10⁹/l	2.86 ± 0.53	2.61 ± 0.68	2.15 ± 0.37	2.47 ± 0.44
MO%	1.44 ± 0.24c	2.02 ± 0.70c	3.48 ± 0.25b	4.46 ± 0.26a
NE%	52.22 ± 4.54ab	46.98 ± 6.27bc	56.52 ± 3.65a	40.76 ± 1.40c
RBC 10¹²/l	7.86 ± 1.10	7.70 ± 0.59	7.82 ± 0.46	7.56 ± 0.69
HGB g/dl	14.4 ± 0.80a	12.46 ± 0.40a	13.68 ± 0.79b	12.56 ± 0.24b
HCT%	37.82 ± 5.10	36.97 ± 3.45	41.04 ± 2.21	37.07 ± 2.23
MCV fl	48.2 ± 1.30ab	47.2 ± 1.64b	50.6 ± 1.34a	50.2 ± 2.59ab
MCH pg	17.42 ± 0.88a	15.44 ± 0.51b	17.1 ± 0.64a	16.4 ± 1.27ab
MCHC g/dl	36.16 ± 1.28a	32.52 ± 1.29b	33.5 ± 0.41b	34.2 ± 1.64ab
RDWc%	18.52 ± 0.65a	18.72 ± 0.75a	16.74 ± 0.69b	17.14 ± 0.51b
PLT 10⁹/l	681 ± 69.56b	729.6 ± 32.25ab	866 ± 143.27a	502.6 ± 90.83c
PCT%	0.52 ± 0.09ab	0.41 ± 0.13b	0.65 ± 0.14a	0.33 ± 0.09b
LYM%	38.22 ± 3.05c	47.34 ± 4.62b	36.42 ± 1.54c	53.36 ± 3.08a
MPV fl	7.6 ± 0.57a	6.92 ± 0.13ab	7.32 ± 0.48ab	6.84 ± 0.29b
PDWc%	34.72 ± 0.97	33.2 ± 0.70	34.36 ± 1.40	33.36 ± 0.59

Data represents the mean ± standard deviation (n = 5). Within columns, means followed by the same letter (a, b or c) are not significantly different between treatment according to the Tuckey’s test (p = 0.05). While, within columns means followed by the different letter (a, b and c) are significantly different between treatments according to the Tuckey’s test (p = 0.05). ns: not significant; significant at the 0.05 probability level

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