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Table 1 Temperature and catalyst amount for the synthesis of 1,8-dioxo-octahydroxanthene

From: Sulfonic acid-functionalized polyallylamine (sevelamer) as an efficient reusable strong solid acid catalyst for the synthesis of xanthenes derivatives

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Entry

T (°C)

Amount of catalyst (g)

Time (min)

Yield (%)a

1

25

0.0100

120

73

2

50

0.0100

120

82

3

70

0.0100

90

91

4

90

0.0100

30

94

5

90

12 h

31

6

90

0.0010

8 h

84

7

90

0.0050

60

90

8

90

0.0100

30

94

9

90

0.0150

30

95

  1. Reaction conditions: 1a (1.0 mmol), 2a (2.0 mmol), S-SO3H (10 mg), water (1.0 mL), 90 °C
  2. aIsolated yield