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Table 2 MBC/MFC (µg ml−1) of diazenyl chalcones (C18–C27) against various microbial strains

From: Antimicrobial, antioxidant and cytotoxic evaluation of diazenyl chalcones along with insights to mechanism of interaction by molecular docking studies

Compound

B. cereus

MBC (µg ml−1)

S. typhi

MBC (µg ml−1)

E. coli

MBC (µg ml−1)

S. aureus

MBC (µg ml−1)

B. subtilis

MBC (µg ml−1)

C. albicans

MFC (µg ml−1)

A. fumigatus

MFC (µg ml−1)

C-18

125

125

62.5

125

125

125

125

C-19

500

125

500

125

62.5

125

250

C-20

125

125

250

125

125

250

125

C-21

62.5

125

31.25

125

62.5

125

125

C-22

3.90

7.81

7.81

31.25

7.81

31.25

125

C-23

62.5

62.5

15.62

125

62.5

125

125

C-24

15.62

15.62

31.25

15.62

62.5

125

125

C-25

125

125

125

62.5

62.5

62.5

62.5

C-26

250

62.5

125

31.25

62.5

125

125

C-27

125

62.5

15.62

62.5

31.25

62.5

125

Dye A

31.25

62.5

31.25

125

125

62.5

125

Dye E

62.5

125

31.25

62.5

125

125

125

Chalcone

62.5

62.5

31.25

62.5

62.5

125

125

Cefadroxil

31.25

125

31.25

31.25

125

–

–

Cefotaxime

15.62

7.81

7.81

31.25

7.81

–

–

SXT

7.81

3.90

1.95

7.81

15.62

–

–

CIP

15.62

7.81

7.81

3.90

15.62

–

–

Fluconazole

–

–

–

–

–

31.25

125

  1. Chalcone (E)-3-(2,4-dichlorophenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one, SXT Sulfamethoxazole/trimethoprim; CIP ciprofloxacin