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Table 1 MIC (µg ml−1) of diazenyl chalcones (C18–C27) against various microbial strains

From: Antimicrobial, antioxidant and cytotoxic evaluation of diazenyl chalcones along with insights to mechanism of interaction by molecular docking studies

Compound

B. cereus

MIC (µg ml−1)

S. typhi

MIC (µg ml−1)

E. coli

MIC (µg ml−1)

S. aureus

MIC (µg ml−1)

B. subtilis

MIC (µg ml−1)

C. albicans

MIC (µg ml−1)

A. fumigatus

MIC (µg ml−1)

C-18

31.25

31.25

15.62

31.25

125

125

125

C-19

500

125

500

125

15.62

125

125

C-20

125

125

125

125

62.5

125

125

C-21

62.5

31.25

15.62

125

31.25

62.5

125

C-22

3.90

3.90

1.95

3.90

1.95

31.25

62.5

C-23

62.5

31.25

15.62

125

62.5

125

62.5

C-24

15.62

7.58

15.62

15.62

31.25

62.5

125

C-25

125

125

62.5

62.5

15.62

31.25

62.5

C-26

250

15.62

62.5

7.81

62.5

125

125

C-27

125

62.5

7.81

62.5

15.62

62.5

125

Dye A

31.25

62.5

15.62

125

125

62.5

125

Dye E

62.5

125

31.25

31.25

62.5

125

125

Chalcone

62.5

31.25

15.62

31.25

62.5

125

125

Cefadroxil

31.25

125

31.25

15.62

62.5

–

–

Cefotaxime

7.81

3.90

7.81

15.62

1.95

–

–

SXT

3.90

3.90

1.95

7.81

7.81

–

–

CIP

7.81

7.81

3.90

1.95

7.81

–

–

Fluconazole

–

–

–

–

–

7.81

15.62

  1. Chalcone (E)-3-(2,4-dichlorophenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one, SXT Sulfamethoxazole/trimethoprim; CIP, ciprofloxacin