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Table 1 MIC (µg ml−1) of diazenyl chalcones (C18C27) against various microbial strains

From: Antimicrobial, antioxidant and cytotoxic evaluation of diazenyl chalcones along with insights to mechanism of interaction by molecular docking studies

Compound B. cereus
MIC (µg ml−1)
S. typhi
MIC (µg ml−1)
E. coli
MIC (µg ml−1)
S. aureus
MIC (µg ml−1)
B. subtilis
MIC (µg ml−1)
C. albicans
MIC (µg ml−1)
A. fumigatus
MIC (µg ml−1)
C-18 31.25 31.25 15.62 31.25 125 125 125
C-19 500 125 500 125 15.62 125 125
C-20 125 125 125 125 62.5 125 125
C-21 62.5 31.25 15.62 125 31.25 62.5 125
C-22 3.90 3.90 1.95 3.90 1.95 31.25 62.5
C-23 62.5 31.25 15.62 125 62.5 125 62.5
C-24 15.62 7.58 15.62 15.62 31.25 62.5 125
C-25 125 125 62.5 62.5 15.62 31.25 62.5
C-26 250 15.62 62.5 7.81 62.5 125 125
C-27 125 62.5 7.81 62.5 15.62 62.5 125
Dye A 31.25 62.5 15.62 125 125 62.5 125
Dye E 62.5 125 31.25 31.25 62.5 125 125
Chalcone 62.5 31.25 15.62 31.25 62.5 125 125
Cefadroxil 31.25 125 31.25 15.62 62.5
Cefotaxime 7.81 3.90 7.81 15.62 1.95
SXT 3.90 3.90 1.95 7.81 7.81
CIP 7.81 7.81 3.90 1.95 7.81
Fluconazole 7.81 15.62
  1. Chalcone (E)-3-(2,4-dichlorophenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one, SXT Sulfamethoxazole/trimethoprim; CIP, ciprofloxacin