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Table 2 Analytical performance data for the determination of FF and GLY by the proposed methods

From: Multiple analytical methods for determination of formoterol and glycopyrronium simultaneously in their novel combined metered dose inhaler

Parameter FF GLY
DS208.27nm RDS214/229nm IPC210nm DS1213.27nm DS2239.86nm RDS240/259nm IPC210nm
Conc. range (μg/mL) 0.48–9.6 0.48–9.6 0.048–4.8 0.9–18 0.9–18 0.9–18 0.09–0.9
r 0.9999 0.9999 0.9999 0.9999 0.9999 0.9999 0.9999
Slope 0.033 0.87 20.8 0.01 0.013 0.36 49.26
Intercept − 0.014 0.99 − 0.22 0.02 0.002 − 0.23 3.76
LOD (μg/mL) 0.06 0.04 0.018 0.15 0.08 0.17 0.051
LOQ (μg/mL) 0.19 0.1 0.055 0.46 0.28 0.52 0.154
Sy/x 9.00 × 10−4 1.4 × 10−3 0.19 7.00 × 10−4 4.00 × 10−4 26.6 × 10−3 1.31
Sa 6.00 × 10−4 1.00 × 10−3 0.11 5.00 × 10−4 3.00 × 10−4 18.6 × 10−3 0.76
Sb 1.00 × 10−4 2.00 × 10−4 0.04 4.80 × 10−5 2.7 × 10−5 1.8 × 10−3 0.16
% RSD 0.49 0.18 0.63 0.69 0.35 0.63 0.54
% Error 0.15 0.06 0.2 0.22 0.11 0.2 0.17
  1. N.B.—Sy/x = standard deviation of the residuals
  2. Sa = standard deviation of the intercept of regression line
  3. Sb = standard deviation of the slope of regression line
  4. % Error = RSD%/√n