From: In silico design and synthesis of targeted rutin derivatives as xanthine oxidase inhibitors
Compound | IC50 (µM) ± SEM | IC50 (µM) ± SEM |
---|---|---|
RU3a1 | 05.021 ± 0.10 | 09.134 ± 0.35 |
RU3a2 | 08.728 ± 0.02 | 04.146 ± 0.01 |
RU3a3 | 11.688 ± 0.01 | 06.561 ± 0.10 |
RU4b1 | 02.647 ± 0.09 | 09.863 ± 0.25 |
RU4b2 | 08.476 ± 0.25 | 04.378 ± 0.01 |
RU7c1 | 06.056 ± 0.13 | 14.731 ± 0.60 |
RU7c2 | 14.669 ± 0.01 | 12.126 ± 0.20 |
RU7c3 | 07.692 ± 0.42 | 17.884 ± 0.41 |
RU001 | 09.483 ± 0.08 | 18.623 ± 0.07 |
Ascorbic acid | 22.195 ± 0.08 | 22.195 ± 0.08 |