From: In silico design and synthesis of targeted rutin derivatives as xanthine oxidase inhibitors
Compound | IC50 (µM) ± SEM | Compound | IC50 (µM) ± SEM |
---|---|---|---|
Rutin | 20.867 ± 0.12 | RU4b 2 | 12.541 ± 0.45 |
RU3a 1 | 09.924 ± 0.01 | RU7c 1 | 19.377 ± 0.38 |
RU3a 2 | 07.905 ± 0.15 | RU7c 2 | 17.428 ± 0.01 |
RU3a 3 | 04.870 ± 0.02 | RU7c 3 | 13.476 ± 0.25 |
RU4b 1 | 15.037 ± 0.01 | Allopurinol | 10.410 ± 0.72 |