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Table 3 In vitro xanthine oxidase inhibitory activity of rutin derivatives

From: In silico design and synthesis of targeted rutin derivatives as xanthine oxidase inhibitors

Compound IC50 (µM) ± SEM Compound IC50 (µM) ± SEM
Rutin 20.867 ± 0.12 RU4b 2 12.541 ± 0.45
RU3a 1 09.924 ± 0.01 RU7c 1 19.377 ± 0.38
RU3a 2 07.905 ± 0.15 RU7c 2 17.428 ± 0.01
RU3a 3 04.870 ± 0.02 RU7c 3 13.476 ± 0.25
RU4b 1 15.037 ± 0.01 Allopurinol 10.410 ± 0.72
  1. SEM, standard error of the mean