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Table 3 In vitro xanthine oxidase inhibitory activity of rutin derivatives

From: In silico design and synthesis of targeted rutin derivatives as xanthine oxidase inhibitors

Compound

IC50 (µM) ± SEM

Compound

IC50 (µM) ± SEM

Rutin

20.867 ± 0.12

RU4b 2

12.541 ± 0.45

RU3a 1

09.924 ± 0.01

RU7c 1

19.377 ± 0.38

RU3a 2

07.905 ± 0.15

RU7c 2

17.428 ± 0.01

RU3a 3

04.870 ± 0.02

RU7c 3

13.476 ± 0.25

RU4b 1

15.037 ± 0.01

Allopurinol

10.410 ± 0.72

  1. SEM, standard error of the mean