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Table 4 Antiproliferative activity of compound 4a

From: Benzimidazole scaffolds as promising antiproliferative agents: a review

Compound

Cancer cell lines (Log GI50)

L

NSCLC

CC

CNSC

M

OC

RC

PC

BC

MG-MID

X

− 5.48

− 5.17

− 5.11

− 5.12

− 5.08

− 5.18

− 4.99

− 4.49

− 4.79

− 5.09

Y

− 6.39

− 6.20

− 6.14

− 6.18

− 6.08

− 6.45

− 6.17

− 6.41

− 6.05

− 6.20

4a

− 6.40

− 4.40

− 4.00

− 4.92

− 4.47

− 4.00

− 4.00

− 4.00

− 4.62

− 4.63

  1. X: Melphalan; Y: cis-diaminedichloroplatinum