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Table 4 Antiproliferative activity of compound 4a

From: Benzimidazole scaffolds as promising antiproliferative agents: a review

Compound Cancer cell lines (Log GI50)
L NSCLC CC CNSC M OC RC PC BC MG-MID
X − 5.48 − 5.17 − 5.11 − 5.12 − 5.08 − 5.18 − 4.99 − 4.49 − 4.79 − 5.09
Y − 6.39 − 6.20 − 6.14 − 6.18 − 6.08 − 6.45 − 6.17 − 6.41 − 6.05 − 6.20
4a − 6.40 − 4.40 − 4.00 − 4.92 − 4.47 − 4.00 − 4.00 − 4.00 − 4.62 − 4.63
  1. X: Melphalan; Y: cis-diaminedichloroplatinum