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Table 13 Anticancer activity results (IC50 and IC90 µM) of compounds (25a25e)

From: Benzimidazole scaffolds as promising antiproliferative agents: a review

Compounds Cancer cell lines IC50 Doxorubicin IC90 Doxorubicin
25a HEPG2 0.55 ± 0.05 0.59 ± 0.03 7.53 ± 0.06 6.82 ± 0.06
25b HEPG2 0.55 ± 0.03 0.59 ± 0.03 7.62 ± 0.09 6.82 ± 0.06
25c MCF7 2.15 ± 0.04 0.72 ± 0.08 11.70 ± 0.17 8.77 ± 0.06
25d MCF7 2.83 ± 0.03 0.72 ± 0.08 12.63 ± 0.09 8.77 ± 0.06
HCT 116 3.72 ± 0.03 0.65 ± 0.09 12.02 ± 0.07 7.32 ± 0.09
25e MCF7 2.85 ± 0.15 0.65 ± 0.09 13.25 ± 0.13 8.77 ± 0.06
HCT 116 3.75 ± 0.16 0.72 ± 0.08 12.05 ± 0.06 7.32 ± 0.09