Table 11 Antitumor activity results of compounds (20a–20c)
From: Benzimidazole scaffolds as promising antiproliferative agents: a review
Compounds | Activity (µM) | MG-MID |
|---|---|---|
20a | GI50 | 1.64 |
TGI | 3.28 | |
LC50 | 5.50 | |
20b | GI50 | 0.81 |
TGI | 2.08 | |
LC50 | 4.47 | |
20c | GI50 | 4.52 |
TGI | 15.9 | |
LC50 | 57.1 | |
Quinazoline analogue | GI50 | 16.9 |
TGI | 40.5 | |
LC50 | > 100 | |
Benzimidazole analogue | GI50 | 18.1 |
TGI | 33.4 | |
LC50 | 56.7 |