Table 5 Percentage control growth against human lung cancer cell line A-549
1.00 | Human lung cancer cell line A-549 | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
% control growth | ||||||||||||||||
Molar drug concentrations | ||||||||||||||||
Experiment 1 | Experiment 2 | Experiment 3 | Average values | |||||||||||||
10−7 M | 10−6 M | 10−5 M | 10−4 M | 10−7 M | 10−6 M | 10−5 M | 10−4 M | 10−7 M | 10−6 M | 10−5 M | 10−4 M | 10−7 M | 10−6 M | 10−5 M | 10−4 M | |
S6 | 106.9 | 127.4 | 126.8 | 60.4 | 134.1 | 122.0 | 144.3 | 79.4 | 131.3 | 130.6 | 131.0 | 72.2 | 124.1 | 126.6 | 134.0 | 70.7 |
S7 | 111.0 | 127.1 | 127.4 | 71.5 | 147.4 | 126.6 | 136.2 | 90.1 | 130.6 | 128.7 | 127.1 | 90.5 | 129.7 | 127.5 | 130.2 | 84.0 |
S8 | 101.4 | 131.3 | 126.3 | 33.1 | 134.7 | 115.2 | 127.0 | 45.7 | 130.2 | 129.1 | 132.3 | 55.7 | 122.1 | 125.2 | 128.5 | 44.8 |
S9 | 103.6 | 111.0 | 126.1 | 53.8 | 117.0 | 98.5 | 125.0 | 58.4 | 124.9 | 114.8 | 136.4 | 66.3 | 115.2 | 108.1 | 129.2 | 59.5 |
S10 | 106.8 | 129.6 | 123.0 | 43.1 | 140.2 | 113.2 | 122.9 | 44.9 | 128.4 | 134.1 | 130.6 | 66.7 | 125.1 | 125.6 | 125.5 | 51.6 |
ADR | 58.0 | 25.8 | − 0.2 | − 20.2 | 9.3 | 25.4 | − 1.6 | − 12.8 | 0.7 | 26.3 | 7.1 | 0.3 | 22.6 | 25.8 | 1.8 | − 10.9 |