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Table 3 NO inhibitory activity of the new compounds (1–3) from aerial part of Tirpitzia sinensis

From: Three new compounds with nitric oxide inhibitory activity from Tirpitzia sinensis, an ethnomedicinal plant from Southwest China

Compound Dose (μM) NO inhibition rate (%) IC a50 (μM)
1 0.1 0 14.97 ± 0.87
  1 11.97 ± 0.41  
  10 36.47 ± 2.37  
2 0.1 0 26.63 ± 1.32
  1 7.40 ± 1.68  
  10 20.10 ± 0.43  
3 0.1 3.93 ± 0.57 17.09 ± 2.3
  1 18.04 ± 1.93  
  10 23.33 ± 2.42  
  1. aThe concentrations of compounds that gave 50% inhibiting potential was calculated by modified Kou type equation: lgIC50 = Xm − I(P − (3 − Pm − Pn)/4). Positive control (curcumin) gave an IC50 value of 4.75 μΜ