Skip to main content

Table 4 Anticancer screening results of synthesized derivatives

From: Design, synthesis and biological profile of heterocyclic benzimidazole analogues as prospective antimicrobial and antiproliferative agents

Anticancer screening

Comp.

IC50 (μM)

Comp.

IC50 (μM)

Z1

214.30

Z16

> 281.37

Z2

> 304.51

Z17

140.69

Z3

> 304.51

Z18

121.83

Z4

220.87

Z19

> 280.58

Z5

220.87

Z20

> 269.98

Z6

179.16

Z21

> 256.87

Z7

> 314.66

Z22

> 306.37

Z8

314.66

Z23

> 269.98

Z9

> 321.13

Z24

0.46

Z10

152.70

Z25

78.25

Z11

> 331.90

Z26

198.08

Z12

> 331.90

Z27

67.49

Z13

336.25

Z28

> 290.02

Z14

> 321.13

Z29

252.68

Z15

> 336.25

Z30

> 293.77

5-Fluorouracil

8.84

5-Fluorouracil

8.84