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Table 4 Anticancer screening results of synthesized derivatives

From: Design, synthesis and biological profile of heterocyclic benzimidazole analogues as prospective antimicrobial and antiproliferative agents

Anticancer screening
Comp. IC50 (μM) Comp. IC50 (μM)
Z1 214.30 Z16 > 281.37
Z2 > 304.51 Z17 140.69
Z3 > 304.51 Z18 121.83
Z4 220.87 Z19 > 280.58
Z5 220.87 Z20 > 269.98
Z6 179.16 Z21 > 256.87
Z7 > 314.66 Z22 > 306.37
Z8 314.66 Z23 > 269.98
Z9 > 321.13 Z24 0.46
Z10 152.70 Z25 78.25
Z11 > 331.90 Z26 198.08
Z12 > 331.90 Z27 67.49
Z13 336.25 Z28 > 290.02
Z14 > 321.13 Z29 252.68
Z15 > 336.25 Z30 > 293.77
5-Fluorouracil 8.84 5-Fluorouracil 8.84