Synthesis, molecular modelling and biological significance of N-(4-(4-bromophenyl) thiazol-2-yl)-2-chloroacetamide derivatives as prospective antimicrobial and antiproliferative agents

Table 1 Physicochemical characteristics of the synthesized compounds (d1–d9)

S. No.	Molecular formula	M. Wt.	M.P. (^oC)	R_f value^a	% Yield
1.	C₁₇H₁₂BrClN₄O₃S	468	105–107	0.36	73
2.	C₁₇H₁₂BrClN₄O₃S	468	88–90	0.26	68
3.	C₁₇H₁₃Br₂N₃OS	467	118–120	0.41	71
4.	C₁₇H₁₃BrN₄O₃S	433	103–105	0.24	68
5.	C₁₇H₁₃BrClN₃OS	407	118–120	0.36	87
6.	C₁₈H₁₅BrN₄O₃S	447	75–77	0.27	76
7.	C₁₇H₁₃BrN₄O₃S	418	108–110	0.32	66
8.	C₁₇H₁₂BrClN₄O₃S	452	78–80	0.22	65
9.	C₁₈H₁₅BrN₄O₃S	432	110–112	0.41	77

ISSN: 2661-801X