Table 2 Scope of the reaction
From: Synthesis of (1E,3E)-1,4-diarylbuta-1,3-dienes promoted by μ-OMs palladium–dimer complex
Entrya | R1 | R2 | Product | t/h | Yield/%b |
|---|---|---|---|---|---|
1 | H | 4-Cl | 3b | 18 | 82 |
2 | H | 3-Cl | 3c | 18 | 61 |
3 | H | 2-Cl | 3d | 24 | 58 |
4 | H | 4-CH3 | 3e | 18 | 68 |
5 | 4-Cl | H | 3b | 24 | 75 |
6 | 4-OCH3 | H | 3f | 36 | 55 |
7 | 4-F | H | 3g | 18 | 82 |
8 | 4-CH3 | H | 3e | 18 | 68 |
9 | 4-OCOCH3 | H | 3h | 30 | 54 |
10 | 4-Br | H | – | 24 | Mixture |
11 | 4-Cl, R′ = Me | H | 3i | 18 | 65 |
12 | 4-F | 4-Cl | 3j | 24 | 71 |
13 | 4-Cl | 4-Cl | 3k | 24 | 63 |
14 | 4-CH3 | 3-Cl | 3l | 18 | 66 |
15 | 4-CH3 | 4-Cl | 3m | 20 | 74 |
16 | 4-F | 4-Br | 3n | 24 | 61 |