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Table 7 H2O2 scavenging activity of eugenol derivatives

From: Lead optimization for promising monoamine oxidase inhibitor from eugenol for the treatment of neurological disorder: synthesis and in silico based study

Compound/sample

IC50 (µg/mL)a

Sr. no

IC50 (µg/mL)a

5a

9.156 ± 0.002

13a

26.6 ± 0.544

5b

8.904 ± 0.034

13b

12.5 ± 0.862

7

9.755 ± 0.021

13c

15.7 ± 0.784

9a

9.547 ± 0.051

13d

14.4 ± 0.143

9b

9.393 ± 0.017

16

20.6 ± 0.856

11

10.33 ± 0.022

17

30.4 ± 0.064

Eugenol

9.980 ± 0.012

l-Ascorbic acid

8.121 ± 0.082

  1. aValue are expressed as mean ± SEM, n = 3
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BMC Chemistry

ISSN: 2661-801X

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