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Table 6 Cytotoxicity of compounds with Schizonticidal compounds against HEK-293 cells

From: Docking predictions based Plasmodium falciparum phosphoethanolamine methyl transferase inhibitor identification and in-vitro antimalarial activity analysis

S. no. Comp. id IC50 schizonticidal (µM) LD50 cyto-toxicity (µM) Safety index (LD50/IC50)
1 ZINC02103914 3.0 77.12 25.83
2 ZINC12882412 2.1 68.54 32.63