Table 6 Cytotoxicity of compounds with Schizonticidal compounds against HEK-293 cells
S. no. | Comp. id | IC50 schizonticidal (µM) | LD50 cyto-toxicity (µM) | Safety index (LD50/IC50) |
|---|---|---|---|---|
1 | ZINC02103914 | 3.0 | 77.12 | 25.83 |
2 | ZINC12882412 | 2.1 | 68.54 | 32.63 |
S. no. | Comp. id | IC50 schizonticidal (µM) | LD50 cyto-toxicity (µM) | Safety index (LD50/IC50) |
|---|---|---|---|---|
1 | ZINC02103914 | 3.0 | 77.12 | 25.83 |
2 | ZINC12882412 | 2.1 | 68.54 | 32.63 |