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Table 5 Comparison of dried versus liquid urine analysis (n = 18)

From: Evaluating urinary estrogen and progesterone metabolites using dried filter paper samples and gas chromatography with tandem mass spectrometry (GC–MS/MS)

Variable Dried Liquid Difference [95% confidence interval] ICC
Estradiol (ng/mg-Cr) 1.32 (0.70, 3.26) 1.29 (0.74, 3.36) − 0.09 [− 0.19, 0.01] 0.99
Estrone (ng/mg-Cr) 10.78 (6.26, 18.73) 12.78 (7.22, 20.65) − 1.28 [− 2.47, − 0.09]* 0.96
5α-pregnanediol (ng/mg-Cr) 65.81 (27.49, 257.23) 62.29 (32.18, 248.25) − 5.72 [− 29.16, 17.71] 0.98
5β-pregnanediol (ng/mg-Cr) 243.90 (99.22, 408.88) 270.25 (135.96, 400.42) − 98.67 [− 211.46, 14.13]* 0.94
  1. Data presented as median (IQR)
  2. Differences were calculated using a signed rank test (dried-liquid assay), as variables were not normally distributed
  3. ICC intraclass correlation coefficient
  4. * p = 0.04