Entry | R1 | R2 | X | Product | Time (min) | Yielda (%) | Mp (°C) | |
---|---|---|---|---|---|---|---|---|
Found | Reported | |||||||
1 | C6H5 | Et | O | 4a | 10 | 99 | 201–202 | 201 [19] |
2 | 4-ClC6H4 | Et | O | 4b | 10 | 98 | 210–212 | 213 [36] |
3 | 3-O2NC6H4 | Et | O | 4c | 10 | 97 | 225–226 | 224–226 [36] |
4 | 4-O2NC6H4 | Et | O | 4d | 10 | 98 | 208–209 | 206–208 [36] |
5 | 2,4-(Cl)2C6H3 | Et | O | 4e | 10 | 95 | 248–250 | 248–250 [32] |
6 | 4-OHC6H4 | Et | O | 4f | 12 | 90 | 230–231 | 231–233 [36] |
7 | 3,4,5-(CH3O)3C6H2 | Et | O | 4g | 10 | 87 | 178–180 | 178–180 [37] |
8 | 3-OHC6H4 | Et | O | 4h | 15 | 85 | 222–223 | 221 [19] |
9 | 3,4-(OH)2C6H3 | Et | O | 4i | 20 | 80 | 247–248 | 243–244 [38] |
10 | 4-FC6H4 | Et | O | 4j | 10 | 99 | 181–182 | 181–183 [39] |
11 | 4-BrC6H4 | Et | O | 4k | 10 | 98 | 215–217 | 213 [19] |
12 | 2-OHC6H4 | Et | O | 4l | 15 | 92 | 201–203 | 198–200 [37] |
13 | 2-Thienyl | Et | O | 4m | 15 | 95 | 203–204 | 200–202 [40] |
14 | 2-Pyridyl | Et | O | 4n | 15 | 95 | 181–183 | 182–184 [40] |
15 | 2-Furanyl | Et | O | 4o | 10 | 95 | 212–213 | 211–213 [40] |
16 | C6H5 | Et | S | 4p | 10 | 98 | 204–205 | 203 [19] |
17 | 4-FC6H4 | Et | S | 4q | 10 | 96 | 180–181 | 179–181 [39] |
18 | 3-OHC6H4 | Et | S | 4r | 20 | 82 | 184–186 | 184–186 [37] |
19 | C6H4 | Me | O | 4s | 10 | 98 | 215–218 | 215–218 [36] |
20 | 4-ClC6H4 | Me | O | 4t | 10 | 97 | 204–206 | 205–207 [36] |
21 | 4-MeC6H4 | Et | O | 4u | 10 | 92 | 208–210 | 209–210 [36] |
22 | 3-OHC6H4 | Me | O | 4v | 15 | 84 | 224–225 | 222 [19] |
23 | C6H4 | Me | S | 4w | 10 | 97 | 224–227 | 222–224 [36] |