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Table 4 Synthesis of DHPMs 4aw by using Fe3O4@PVA-SO3H under refluxing conditions

From: Design and preparation of Fe3O4@PVA polymeric magnetic nanocomposite film and surface coating by sulfonic acid via in situ methods and evaluation of its catalytic performance in the synthesis of dihydropyrimidines

Entry R1 R2 X Product Time (min) Yielda (%) Mp (°C)
Found Reported
1 C6H5 Et O 4a 10 99 201–202 201 [19]
2 4-ClC6H4 Et O 4b 10 98 210–212 213 [36]
3 3-O2NC6H4 Et O 4c 10 97 225–226 224–226 [36]
4 4-O2NC6H4 Et O 4d 10 98 208–209 206–208 [36]
5 2,4-(Cl)2C6H3 Et O 4e 10 95 248–250 248–250 [32]
6 4-OHC6H4 Et O 4f 12 90 230–231 231–233 [36]
7 3,4,5-(CH3O)3C6H2 Et O 4g 10 87 178–180 178–180 [37]
8 3-OHC6H4 Et O 4h 15 85 222–223 221 [19]
9 3,4-(OH)2C6H3 Et O 4i 20 80 247–248 243–244 [38]
10 4-FC6H4 Et O 4j 10 99 181–182 181–183 [39]
11 4-BrC6H4 Et O 4k 10 98 215–217 213 [19]
12 2-OHC6H4 Et O 4l 15 92 201–203 198–200 [37]
13 2-Thienyl Et O 4m 15 95 203–204 200–202 [40]
14 2-Pyridyl Et O 4n 15 95 181–183 182–184 [40]
15 2-Furanyl Et O 4o 10 95 212–213 211–213 [40]
16 C6H5 Et S 4p 10 98 204–205 203 [19]
17 4-FC6H4 Et S 4q 10 96 180–181 179–181 [39]
18 3-OHC6H4 Et S 4r 20 82 184–186 184–186 [37]
19 C6H4 Me O 4s 10 98 215–218 215–218 [36]
20 4-ClC6H4 Me O 4t 10 97 204–206 205–207 [36]
21 4-MeC6H4 Et O 4u 10 92 208–210 209–210 [36]
22 3-OHC6H4 Me O 4v 15 84 224–225 222 [19]
23 C6H4 Me S 4w 10 97 224–227 222–224 [36]
  1. aIsolated yield