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Table 4 Lethal dose and selectivity index calculation of most active compounds (N9 and N18)

From: 4-(2-(1H-Benzo[d]imidazol-2-ylthio)acetamido)-N-(substituted phenyl)benzamides: design, synthesis and biological evaluation

Compound

Lethal dose (LD50)

IC50

Selectivity index (LD50/IC50)

N9

8.43

5.85

1.44

N18

8.22

4.53

1.81