Antitumor effect of proanthocyanidin induced apoptosis in human colorectal cancer (HT-29) cells and its molecular docking studies

Table 1 Glide XP analysis of proanthocyanidin and 5-fluorouracil

Proteins	XP analysis of docking scores
	Proanthocyanidin				5-Fluorouracil
	Docking score	Glide E model energy	H-bonds	Interacting residue	Docking score	Glide E model energy	H-bonds	Interacting residue
BCL-2	− 4.51	− 42.19	5	Arg105, Glu95, Asp99	− 3.72	− 23.67	2	Asp99
BCL-XL	− 5.23	− 65.83	2	Asp107, Ala104	− 4.43	− 20.79	2	Trp1337, Gly138
CDK2	− 5.17	− 60.94	3	Asp86, Asn132, Glu8	− 4.47	− 25.05	2	Leu83
CDK4	− 4.23	− 27.17	3	Asp97, Thr177, Lys142	− 4.77	− 33.76	2	Lys142, Tyr117

ISSN: 2661-801X