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Table 3 Cytotoxicity activity of porphyrin and its complexes

From: Synthesis and bioactivity of oxovanadium(IV)tetra(4-methoxyphenyl)porphyrinsalicylates

Groups (% growth inhibition)
Conc. Lung (A549) Glioblastoma (T98G) Prostate (PC3) Breast (T47D)
TMP 1 × 10−4 M 13 15 17 14
VO(TMP) 1 × 10−4 M 15 18 20 17
(SA)VO(TMP) 1 × 10−4 M 25 35 25 27
(SSA)VO(TMP) 1 × 10−4 M 45 75 55 27
SA 1 × 10−4 M 18 21 20 15
SSA 1 × 10−4 M 21 22 24 20
Paclitaxel 1 µM 65
Mitomycin-c 1 µM 68
Adriamycin 1 µM 59 73
  1. TMP tetra(4-methoxyphenyl)porphyrin, VO(TMP) oxovanadium(IV)tetra(4-methoxyphenyl)porphyrin, [VO(TMP)SA] oxovanadium(IV)tetra(4-methoxyphenyl)porphyrinsalicylate, [VO(TMP)SSA] oxovanadium(IV)tetra(4-methoxyphenyl)porphyrinsulphosalicylate