Table 3 Cytotoxicity activity of porphyrin and its complexes
From: Synthesis and bioactivity of oxovanadium(IV)tetra(4-methoxyphenyl)porphyrinsalicylates
Groups | (% growth inhibition) | ||||
|---|---|---|---|---|---|
Conc. | Lung (A549) | Glioblastoma (T98G) | Prostate (PC3) | Breast (T47D) | |
TMP | 1 × 10−4 M | 13 | 15 | 17 | 14 |
VO(TMP) | 1 × 10−4 M | 15 | 18 | 20 | 17 |
(SA)VO(TMP) | 1 × 10−4 M | 25 | 35 | 25 | 27 |
(SSA)VO(TMP) | 1 × 10−4 M | 45 | 75 | 55 | 27 |
SA | 1 × 10−4 M | 18 | 21 | 20 | 15 |
SSA | 1 × 10−4 M | 21 | 22 | 24 | 20 |
Paclitaxel | 1 µM | 65 | – | – | – |
Mitomycin-c | 1 µM | – | – | 68 | – |
Adriamycin | 1 µM | – | 59 | – | 73 |