Table 7 Antimicrobial activity results of compounds (8a–8e)
From: Antimicrobial potential of 1H-benzo[d]imidazole scaffold: a review
Comp. | Microorganisms (MIC = µg/mL) | ||||||
|---|---|---|---|---|---|---|---|
S. aureus | S. pyrogens | E. coli | P. aeruginosa | C. albicans | A. niger | A. clavatus | |
8a | 12.5 ± 1.05 | 12.5 ± 1.21 | 25 ± 1.35 | 25 ± 2.80 | 500 ± 1.57 | 100 ± 1.24 | 250 ± 2.78 |
8b | 50 ± 1.54 | 50 ± 1.31 | 100 ± 2.65 | 100 ± 1.61 | 500 ± 2.15 | 250 ± 2.21 | 250 ± 1.24 |
8c | 12.5 ± 1.48 | 25 ± 2.15 | 25 ± 1.35 | 25 ± 1.15 | 100 ± 1.64 | 500 ± 1.85 | 250 ± 1.32 |
8d | 25 ± 1.21 | 50 ± 1.81 | 25 ± 1.54 | 50 ± 1.51 | 250 ± 1.32 | > 1000 | 500 ± 2.32 |
8e | 62.5 ± 1.35 | 100 ± 1.65 | 125 ± 1.42 | 125 ± 1.71 | 25 ± 1.41 | 50 ± 1.14 | 62.5 ± 1.35 |
Chloram-phenicol | 50 ± 1.24 | 50 ± 2.04 | 50 ± 1.00 | 50 ± 2.06 | – | – | – |
Ketoconazole | – | – | – | – | 50 ± 0.50 | 50 ± 1.20 | 50 ± 1.10 |