Table 2 Data of the in vitro studies for M. tuberculosis (H37Rv) and docking score of synthesized compounds
Compound ID | Antitubercular activity MIC (μmol/L) on H37RV | Docking score | Compound ID | Antitubercular activity MIC (μmol/L) on H37RV | Docking score |
|---|---|---|---|---|---|
5a | 1.2 | − 7.234 | 5m | 1.7 | − 6.964 |
5b | 1.5 | − 7.140 | 5n | 1.2 | − 5.761 |
5c | 0.6 | − 7.500 | 5o | 1.1 | − 6.657 |
5d | 1.1 | − 7.400 | 5p | 1.5 | − 6.193 |
5e | 1.7 | − 6.695 | 5q | 1.4 | − 6.186 |
5f | 2.3 | − 7.081 | 5r | 1.6 | − 7.084 |
5g | 0.5 | − 7.698 | 5s | 1.4 | − 5.793 |
5h | 1.1 | − 7.286 | 5t | 1.8 | − 5.761 |
5i | 0.8 | − 8.825 | 5u | 0.7 | − 8.213 |
5j | 2.1 | − 7.611 | 5v | 2.6 | − 6.657 |
5k | 1.9 | − 6.685 | 5w | 1.0 | − 5.836 |
5l | 1.3 | − 5.761 | Isoniazid | 0.3 | − 7.328 |