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Table 2 Data of the in vitro studies for M. tuberculosis (H37Rv) and docking score of synthesized compounds

From: Synthesis, biological evaluation and molecular docking studies of 6-(4-nitrophenoxy)-1H-imidazo[4,5-b]pyridine derivatives as novel antitubercular agents: future DprE1 inhibitors

Compound ID Antitubercular activity MIC (μmol/L) on H37RV Docking score Compound ID Antitubercular activity MIC (μmol/L) on H37RV Docking score
5a 1.2 − 7.234 5m 1.7 − 6.964
5b 1.5 − 7.140 5n 1.2 − 5.761
5c 0.6 − 7.500 5o 1.1 − 6.657
5d 1.1 − 7.400 5p 1.5 − 6.193
5e 1.7 − 6.695 5q 1.4 − 6.186
5f 2.3 − 7.081 5r 1.6 − 7.084
5g 0.5 − 7.698 5s 1.4 − 5.793
5h 1.1 − 7.286 5t 1.8 − 5.761
5i 0.8 − 8.825 5u 0.7 − 8.213
5j 2.1 − 7.611 5v 2.6 − 6.657
5k 1.9 − 6.685 5w 1.0 − 5.836
5l 1.3 − 5.761 Isoniazid 0.3 − 7.328