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Table 24 Urease inhibition studies of 5-arylthiophene-2-sulfonylacetamides

From: Therapeutic importance of synthetic thiophene

Compound Percentage activity at 15 µg/ml Percentage activity at 40 µg/ml Percentage activity at 80 µg/ml IC50 µg/ml
112 42.44 ± 0.11 92.12 ± 0.21 94.66 ± 0.11 17.1 ± 0.15
Standard 47.1 ± 0.31 65 ± 0.01 23.3 ± 0.21
  1. Standard = Thiourea