Table 24 Urease inhibition studies of 5-arylthiophene-2-sulfonylacetamides
Compound | Percentage activity at 15 µg/ml | Percentage activity at 40 µg/ml | Percentage activity at 80 µg/ml | IC50 µg/ml |
|---|---|---|---|---|
112 | 42.44 ± 0.11 | 92.12 ± 0.21 | 94.66 ± 0.11 | 17.1 ± 0.15 |
Standard | 47.1 ± 0.31 | 65 ± 0.01 | – | 23.3 ± 0.21 |