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Table 21 Anti-inflammatory activity of the synthesized compounds

From: Therapeutic importance of synthetic thiophene

Compounds Edema inhibition (means ± E.M)a,b (%)
1 h 2 h 3 h
94 42.3 ± 1.1 49.2 ± 1.2 57.1 ± 1.4
95 37.2 ± 1.3 46.3 ± 1.5 54.4 ± 1.1
96 34.5 ± 1.2 35.1 ± 1.5 48.2 ± 1.2
97 31.2 ± 1.2 35.1 ± 1.5 40.2 ± 1.6
98 39.1 ± 1.5 48.4 ± 1.2 55.6 ± 1.1
Indomethacin 44.7 ± 1.2 52.4 ± 1.2 61.2 ± 1.3
  1. aDose 5 mg/kg b.m (p.o.)
  2. b n = 6