Compound | IC50 (μmol/l)a | |||
---|---|---|---|---|
MCF-7 | NCI-H460 | SF-268 | WI-38 | |
74 | 0.03 ± 0.007 | 0.02 ± 0.008 | 0.01 ± 0.004 | > 100 |
76b | 0.01 ± 0.006 | 0.03 ± 0.002 | 0.06 ± 0.005 | > 100 |
77 | 0.01 ± 0.003 | 0.02 ± 0.001 | 0.01 ± 0.001 | 66.5 ± 12.7 |
DSMO | 94.3 ± 6.4 | 96.4 ± 10.2 | 98.6 ± 12.2 | > 100 |
Doxorubicin | 0.0428 ± 0.0082 | 0.0940 ± 0.0087 | 0.0940 ± 0.0070 | > 100 |