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Table 4 Estimated exposures (ng/person/day) to coumarin from Swedish and US STPs

From: Analysis of coumarin and angelica lactones in smokeless tobacco products

STP Coumarin concentration by brand (ng/g) STP consumption (g/day) Extraction in mouth (%) Exposure (ng/day) (using highest reported consumption rate)
Min Max Min Max
Swedish P snus < 30 486 14.4b, 11–12c 24 < 104 2288
Swedish L snus < 30 331 20.8b, 29–32c 24 < 230 2542
US MSa 206 1033 7.3d, 10e, 12.4f, 5.3g, 20.4h 24 613a 5057a
US DS < 30 3347 N/A 24 N/A N/A
US CT < 30 247 N/A 24 N/A N/A
  1. N/A not available
  2. a Actual exposures may be lower due to expectoration
  3. b Andersson et al. [60]
  4. c Digard et al. [61]
  5. d Maxwell [62]
  6. e Surgeon General [63]
  7. f Hatsukami et al. [64]
  8. g Hecht et al. [67]
  9. h Hecht et al. [65]