Table 5 Docking score and binding energy of compound 6 with standard drug (tamoxifen)
From: Design, synthesis and biological evaluation of 3-(2-aminooxazol-5-yl)-2H-chromen-2-one derivatives
Compound | Docking score | Interacting residues |
|---|---|---|
6 | − 6.462 | ILE424, MET421, LEU525, MET343, LEU346, THR347, A350, ASP351, LEU354, LEU539, LEU536, VAL534, VAL533 |
Tamoxifen | − 11.595 | ASP351, GLU353, LEU354, ALA350, LEU349, THR347, LEU346, MET343, ARG394, LEU391, MET388, LEU387, LEU384, TRP383, LEU536 |