Table 4 Docking score and binding energy of compound 14 with standard drug (5-fluorouracil)
From: Design, synthesis and biological evaluation of 3-(2-aminooxazol-5-yl)-2H-chromen-2-one derivatives
Compound | Docking score | Interacting residues |
|---|---|---|
14 | − 7.491 | ARG356, VAL27, GLY28, LEU359, ALA50, LYS52, VAL35, LEU158, ASP98, PHE97, ALA172, ASP173, PHE176, ALA100, TYR99 |
5-fluorouracil | − 5.753 | LEU158, ARG356, ALA100, TYR99, ASP98, PHE97, ILE79, VAL35, ALA50 |