Table 3 Antimicrobial activity of synthesized compounds
From: Synthesis and biological profile of substituted benzimidazoles
Comp. | Antimicrobial screening (MIC = µM) | ||||
|---|---|---|---|---|---|
Bacterial species | Fungal species | ||||
E. coli | B. subtilis | S. aureus | C. albicans | A. niger | |
1 | 05.4 | 10.7 | 43 | 10.7 | 21.5 |
2 | 43.5 | 21.8 | 43.5 | 5.4 | 10.9 |
3 | 22.2 | 22.2 | 44.4 | 11.1 | 22.2 |
4 | 06.6 | 13.1 | 52.7 | 13.1 | 26.3 |
5 | 46.9 | 23.5 | 46.9 | 23.5 | 23.5 |
6 | 47.3 | 23.6 | 47.3 | 47.3 | 47.3 |
7 | 23.5 | 23.5 | 46.9 | 93.9 | 23.5 |
8 | 39.3 | 39.3 | 78.5 | 78.5 | 78.5 |
9 | 24.9 | 24.9 | 49.7 | 24.9 | 49.7 |
10 | 14.5 | 29 | 58.1 | 29 | 58.1 |
11 | 10.0 | 20.1 | 40.1 | 20.1 | 20.1 |
12 | 248.5 | 248.5 | 15.5 | 62.1 | 31.1 |
13 | 56.1 | 28.1 | 14 | 14 | 7 |
14 | 197.4 | 197.4 | 24.7 | 98.7 | 24.7 |
15 | 194.3 | 194.3 | 24.3 | 48.6 | 24.3 |
16 | 58.0 | 29 | 14.5 | 14.5 | 7.2 |
17 | 28.7 | 28.7 | 14.4 | 28.7 | 7.2 |
18 | 26.9 | 13.4 | 13.4 | 26.9 | 6.7 |
19 | 49.5 | 12.4 | 12.4 | 6.2 | 3.1 |
20 | 45.5 | 11.4 | 22.7 | 22.7 | 11.4 |
21 | 27.9 | 14 | 14 | 55.9 | 7 |
22 | 56.9 | 28.4 | 14.2 | 28.4 | 7.1 |
23 | 60.5 | 30.2 | 15.1 | 30.2 | 7.5 |
24 | 28.6 | 28.6 | 14.3 | 28.6 | 7.1 |
25 | 60.2 | 30.1 | 15 | 30.1 | 7.5 |
26 | 29.7 | 29.7 | 14.9 | 59.5 | 7.4 |
27 | 58.1 | 29 | 14.5 | 29 | 7.2 |
28 | 49.5 | 24.8 | 24.8 | 24.8 | 12.4 |
29 | 47.3 | 11.8 | 23.6 | 23.6 | 11.8 |
30 | 29.9 | 29.9 | 14.9 | 59.7 | 7.5 |
DMSO | NA | NA | NA | NA | NA |
Std. drugs | 4.7a | 4.7a | 4.7a | 5.1b | 5.1b |