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Table 3 Antimicrobial activity of synthesized compounds

From: Synthesis and biological profile of substituted benzimidazoles

Comp. Antimicrobial screening (MIC = µM)
Bacterial species Fungal species
E. coli B. subtilis S. aureus C. albicans A. niger
1 05.4 10.7 43 10.7 21.5
2 43.5 21.8 43.5 5.4 10.9
3 22.2 22.2 44.4 11.1 22.2
4 06.6 13.1 52.7 13.1 26.3
5 46.9 23.5 46.9 23.5 23.5
6 47.3 23.6 47.3 47.3 47.3
7 23.5 23.5 46.9 93.9 23.5
8 39.3 39.3 78.5 78.5 78.5
9 24.9 24.9 49.7 24.9 49.7
10 14.5 29 58.1 29 58.1
11 10.0 20.1 40.1 20.1 20.1
12 248.5 248.5 15.5 62.1 31.1
13 56.1 28.1 14 14 7
14 197.4 197.4 24.7 98.7 24.7
15 194.3 194.3 24.3 48.6 24.3
16 58.0 29 14.5 14.5 7.2
17 28.7 28.7 14.4 28.7 7.2
18 26.9 13.4 13.4 26.9 6.7
19 49.5 12.4 12.4 6.2 3.1
20 45.5 11.4 22.7 22.7 11.4
21 27.9 14 14 55.9 7
22 56.9 28.4 14.2 28.4 7.1
23 60.5 30.2 15.1 30.2 7.5
24 28.6 28.6 14.3 28.6 7.1
25 60.2 30.1 15 30.1 7.5
26 29.7 29.7 14.9 59.5 7.4
27 58.1 29 14.5 29 7.2
28 49.5 24.8 24.8 24.8 12.4
29 47.3 11.8 23.6 23.6 11.8
30 29.9 29.9 14.9 59.7 7.5
DMSO NA NA NA NA NA
Std. drugs 4.7a 4.7a 4.7a 5.1b 5.1b
  1. NA no activity, DMSO dimethyl sulphoxide
  2. Std. drugs: a Norfloxacin, b Fluconazole